Fisher spent her early years in Bathgate before moving with her family to Perth when she was six years old. From 1994 to 1997 she played the role of Shannon Reed on the Australian soap opera Home and Away. After leaving the soap, Fisher enrolled at L’École Internationale de Théâtre Jacques Lecoq, a theatre and arts training school in Paris and went on to appear in pantomime in the United Kingdom. in 2001, Fisher was cast as Kim in the German horror film Swimming Pool. The following year, she portrayed the character Kristy in the Australian comedy The Wannabes. in 2008, she starred in the critically acclaimed romantic comedy film Definitely, Maybe, with Ryan Reynolds, Elizabeth Banks, Rachel Weisz, and Abigail Breslin, and had a voice role in Horton Hears a Who. She starred in the movie adaptation of the book Confessions of a Shopaholic, which opened on 13 February 2009.
